NOW Foods

Turmeric Curcumin Phytosome with Meriva

Evidence: Insufficient

Turmeric / curcumin, rated Limited as an ingredient, 500 mg per serving, below the lowest studied dose of 1,000 mg a day. No USP, NSF or Informed Choice verification shown.

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What studies found on turmeric / curcumin

Limited The only placebo-controlled trial in people with high uric acid (Bupparenoo 2021, n=39) found curcumin no better than placebo, and the positive trial (Panahi 2016, n=87) enrolled people with fatty liver disease, not gout.

Studied dose: 1,000 mg curcumin a day (500 mg twice daily).

  • Bupparenoo P 2021, J Diet Suppl. Randomized placebo-controlled trial, 39 people, 8 weeks. In people with asymptomatic high uric acid, serum urate fell 6.9% on curcumin and 5.0% on placebo, and the difference was not significant.
  • Panahi Y 2016, J Cardiovasc Pharmacol. Randomized controlled trial, 87 people, 8 weeks. In people with nonalcoholic fatty liver disease, serum uric acid fell more on curcumin than in the control group.
  • Halegoua-DeMarzio D 2023, Am J Med. Case series (DILIN registry), 10 people, Cases enrolled 2004 to 2022. The network found 10 cases of turmeric-associated liver injury, 5 hospitalized and 1 fatal, with a strong link to the HLA-B*35:01 gene variant.

Safety: The US Drug-Induced Liver Injury Network reported 10 cases of turmeric-linked liver injury, including 1 death, and 3 of 7 tested products also contained black pepper (PMID 36252717). NCCIH says highly bioavailable curcumin formulations may harm the liver (nccih.nih.gov/health/turmeric, updated April 2025). Talk to your doctor before starting a supplement, especially if you take allopurinol, febuxostat or colchicine.

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